Advanced Bioimaging Technologies in Assessment of the by L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung

By L. Qin, Harry K. Genant, J.F. Griffith, K.S. Leung

This e-book offers a viewpoint at the present prestige of bioimaging applied sciences constructed to evaluate the standard of musculoskeletal tissue with an emphasis on bone and cartilage. It bargains reviews of scaffold biomaterials constructed for reinforcing the fix of musculoskeletal tissues. those bioimaging recommendations contain micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which offer not just 2-D and three-D photographs of the comparable organs or tissues, but additionally quantifications of the appropriate parameters. the development bioimaging applied sciences built for the above functions also are prolonged through incorporating imaging contrast-enhancement fabrics. therefore, this publication will offer a special platform for multidisciplinary collaborations in schooling and joint R&D between a number of professions, together with biomedical engineering, biomaterials, and simple and scientific drugs.

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Extra info for Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications

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Dense vascular network formation adjacent to the defect corner region corresponds with greatest strain energy gradient. a Cross-section at the cortical defect corner. S. Chao Figure 11. The SEM images of cortical defect healing  weeks after surgery. Dense woven bone formation following the vascular network orientation. The defect corner region corresponds to greatest strain energy gradient. a Cross-section at the cortical defect corner. b Longitudinal section across the defect Figure 12. The microradiographs of normal cortical bone defect healing  weeks after surgery.

The remaining  dogs were killed  each at  and  weeks, respectively. A vascular corrosion casting method was used for the microvascular analysis. The specimens were coated gold for SEM study. Routine microradiographic biomechanical and histological analyses were performed for the -week group specimens. A mid-diaphysis length of 5OD was used for the analysis. Identical defect was created in the anterior-medial bone surface. Twenty-node reduced-integration brick elements were used in each FEM model.

In individual patients, specific models can be gen- Bone Structure and Biomechanical Analyses Using Imaging and Simulation Technology 37 erated using innovative scaling techniques to provide unprecedented information to assist physicians and surgeons to optimize treatment and minimize risk. Several computational algorithms, robust model library, and databases are integrated into the VIMS software platform on a SGi super computer main frame under the Unix operating system. All of the independent analysis components of the software are accessible through a single graphical user interface (GUI).

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