Changing Syntheses in Development by Meredith N. Runner

By Meredith N. Runner

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1961). Vegetalization of t h e presumptive ectoderm of Triturus gastrula by exposure t o lithium chloride solution. Embryologia 5 , 384-396. , TIMOFEEVA, Μ . , KUPRIYANOVA, N . , a n d KAFIANI, C. (1969a). Trans­ cription of repetitive D N A sequences in embryogenesis. Mol. Biol. (USSR) 3 , 338-347. , TIMOFEEVA, Μ . , KUPRIYANOVA, N . , a n d KAFIANI, C. (1969b). H o m o l ­ ogies in R N A populations a t different stages of embryogenesis. Mol. Biol. 3 , 486-493. (USSR) G E N E R E D U N D A N C Y A N D CELL DIVISIONS IN E M B R Y O G E N Y 41 REMINGTON, J.

3 4 , 661-680. CLAYTON, R. M . (1968). A re-examination of the organ specificity of lens antigens. Exp. Eye Res. 7 , 11-29. DANIEL, J. C , and FLICKINGER, R. A. (in press). Nuclear D N A - l i k e R N A in developing frog embryos. Exp. Cell Res. D E N I S , H . (1966). Gene expression in amphibian development. I I . Release of t h e genetic information in growing embryos. J. Mol. Biol. 2 2 , 285-304. FLICKINGER, R. A. (1961). T h e effect of ethionine on t h e development of muscular re­ sponse in the frog embryo.

This control could oper- G E N E R E D U N D A N C Y A N D C E L L D I V I S I O N S IN E M B R Y O G E N Y 35 ate by accumulating a sufficient number of genes which will ensure cytoplasmic conservation of the D-RNA molecules responsible for setting the fate of the cells. , 1968). It is possible that transcription of more redundant DNA sequences is primarily responsible for determination of cells whose fate is set after fewer cell divisions. The reduction of number of divisions of gastrula ectoderm by LiCl, together with a slower rate of divisions, results in formation of endoderm or mesoderm.

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