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Additional resources for Difficult Decisions in Hepatobiliary and Pancreatic Surgery: An Evidence-Based Approach (Difficult Decisions in Surgery: An Evidence-Based Approach)
29 88 % (24) of patients and US revealed no recurrences. The evaluation method was not well standardized and enucleation was favored as a safer technique by the authors . 7 % being hemangiomas (10 patients) the most common presenting symptom was pain and enucleation was performed in 64 % of patients. 7 % for the total cohort with no mention on hemangioma related complications . A series from 2001 illustrated the changing indications for resection when patients are analyzed in a large cohort when indications changed (sixe, symptoms etc).
This heterogeneity can be due to differences in the patient population studied, the nature of the intervention, means of measuring outcomes or other study design features. Directness This is the degree to which the studies actually address the question we are interested in. The results may be indirect because the study population is different from one we are interested in or the intervention is differs substantially from what we are interested in. This is slightly different from the above example the indirectness refers to the whole body of evidence in relation to our specific question.
An additional two retrospective single center reviews of resection for hemangioma were included to better assess the rate of complications following resection. The data were classified using the GRADE system. 3) [21–24]. The primary outcomes in most of these studies included perioperative morbidity and mortality, resolution of symptoms in the treatment group or development of new symptoms and adverse events in the observation cohorts. None of the studies describe deliberate changes in treatment algorithms during the study period and no explicit comparison of practices in different eras.